@pike2k It was worse a year ago, I had to make my own LilyGO T-Display S3 (not AMOLED) GitHub repository to help people once I got it figured out.
The one on the left of the schematic image that I sent you is
U0RXD = SCL (GPIO 44) (The 'U' stands for Universal)
U0TXD = SDA (GPIO 43) use Wire.begin(43, 44);
The other connector is marked correctly.
It might have been added as an after thought because the ancient but very common Dallas Semiconductor DS18B20 won't run from the GPIO pins 43 or 44.
ESP32 S3 can use almost any pins for almost any function .
But when setting up I2C you have to call Wire.begin(3, 2);
Or whatever pins you want, within reason. (There is a complicated datasheet for the ESP32 S3 and it points out the only no-no's.)
-Terry